Malnutrition is common in hospitalized patients and is associated with increased morbidity and mortality. However, a single, effective laboratory indicator identifying malnutrition is lacking, although serum proteins, particularly albumin, have often been used. Many variables, including inflammation, are known to affect serum protein markers, decreasing their effectiveness. As a result, many practitioners have replaced albumin with prealbumin as the marker of choice. Although prealbumin is also affected by inflammation, it is now common practice for prealbumin levels to be checked along with a marker of inflammation, in most cases, C-reactive protein.
Immunological testing of the nutrition markers on GPP-100 and uses the principle of measuring absorbance in the cuvette. An optical sensor reads the light that passes through the sample cuvette. The light is absorbed by the fluid in the cuvette in direct proportion to the concentration of antigen-antibody complexes. The amount of light reaching the photodetector is converted into an electrical signal that is proportional or inversely proportional to the analyte concentration.
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