2023-12-15

Her shocking death news soon arise discussions online on the the disease SLE.

What is SLE?

Systemic Lupus Erythematosus (SLE) is a heterogeneous incurable autoimmune disorder characterized by both B- and T-cell dysfunction that results in immune-mediated multi-system tissue damage.

The standard testing criteria for SLE is positice ANA. In 2019, the 2019 EULAR/ACR classification criteria for SLE include positive ANA at least once as obligatory entry criterion; followed by additive weighted criteria grouped in 7 clinical (constitutional, hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal) and 3 immunologic (antiphospholipid antibodies, complement proteins, SLE- specific antibodies) domains, and weighted from 2 to 10. Patients accumulating ≥10 points are classified.The potential implications of having very high scores on disease severity and subsequent prognosis. This multiphase methodologic approach and classification system using a hierarchically clustered criteria established a paradigm shift in the classification of SLE.

Complement activation plays a key role in the pathophysiology of SLE and it is recommended to continue monitoring serum levels of C3 and C4 to assess for disease activity.

GOLDSITE DIGANOSTICS INC. is a leading manufacturer of IVD products dedicated to the healthcare sector. With over 24 years of expertise in the IVD industry, Goldsite has established itself as a trusted partner since 1999. With a team of experts in the field of diagnostics technology and a passion for improving healthcare, we strive to bring cutting-edge products to market that meet the evolving needs of health providers and patients. Engaged in R&D, manufacturing, and marketing of clinical laboratory devices and reagents, Goldsite has a portfolio of products covering specific proteins, chemistry, chemiluminescence, and POCT platform, as well as associated reagents. All products live up to global standards with CE marking and have been exported to more than 80+ countries.

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